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The Research Institute of Chemistry was founded in February 1944 and is currently one of the leading research units of the Lobachevsky Nizhny Novgorod State University.

Among the important areas of research in different years can be called work in the field of:
- creation of a fundamentally new kinetic method of physico-chemical research, as well as effective techniques and devices for analytical purposes;
- chemistry of radioactive elements;
- theories of separation and deep purification of substances;
- relay transmission in radical processes;
- synthesis of (co)polymers;
- development of new approaches to control the growth of the polymer chain;
- rheology, compatibility and phase composition of polymer systems;
- thermodynamics of polymers and MOS and processes involving them;
- chemistry of catalytic processes;
- environmental control of the environment and industrial processes;
- studying the mechanisms of bio systems' resistance to chemical stressors and other adverse factors;
- детоксикации боевых отравляющих веществ и утилизации отходов;
- creation of stabilizers of ethyl liquid, tin-soldering pastes, ski ointments, multifunctional (protective, decorative, strengthening, etc.) coatings, including on the inner surfaces of fuel and energy elements of nuclear reactors, aluminizing electrolytes, low-resistance resistors, thermal protection sensors, biologically active substances, suture materials, non-combustible heat-resistant fiber PAN-ACS, skin fittings, adhesive compositions, food additives, electron and X-ray resists
- and a whole range of other products.

The Institute's activities were closely connected with the most important developments within the framework of various scientific and technological projects: "Protective coatings", "Products of low-tonnage chemistry", "Food", "Regionology", "Reagent", "Agrocomplex", "Platinum metals", "Magnetic liquids", "High-temperature superconductivity", "Man and the Environment", "Conversion", "Fullerenes and atomic clusters", "Electronics", etc.